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West Midlands Cancer Alliance
  • Home
  • About us
    • About the West Midlands Cancer Alliance
    • Who We Are
    • Meet the Team
    • News
    • Newsletters
    • Contact
  • Our work
    • Early Diagnosis
    • Treatment and Care
    • Health Inequalities and Community Engagement
    • Innovation
  • Patients' area
    • Patient and Public Resources
    • How to Get Involved
    • Patient Advocates
    • External Patient Groups
    • Common side effects of non-surgical cancer treatments
    • Patient Surveys
    • Patient Information
    • Video Library
  • Professionals' area
    • Primary Care Resources, Learning and Development
    • Clinical Resources
    • Health Inequalities Resources
    • Expert Advisory Groups
    • Operational Delivery Network
    • Performance Standards
    • Midlands Cancer Alliances Life Sciences Hub
  • Cancer Academy
    • WMCA Cancer Careers and Education programme
    • ePortfolio
    • Upcoming training
    • Additional learning resources
    • Digital Poster Library
    • ACCEND Implementation

Expert Advisory Groups

AO, MSCC and CUP

  • Primary Care Resources, Learning and Development
    • Screening and Early Diagnosis Resources
    • Tumour Site Specific Resources
    • Urgent Suspected Cancer Referral Forms
    • Prostate Toolkit
      • Why This MattersWhy This Matters
      • Take Action in Your PracticeTake Action in Your Practice
      • Quick Clinical GuideQuick Clinical Guide
      • Communication and System ToolsCommunication and System Tools
      • Awareness CampaignsAwareness Campaigns
      • Patient StoriesPatient Stories
      • Primary Care Best PracticePrimary Care Best Practice
      • Ready-to-Use ResourcesReady-to-Use Resources
      • Education and TrainingEducation and Training
      • Key ContactsKey Contacts
  • Clinical Resources
  • Health Inequalities Resources
  • Expert Advisory Groups
    • Acute Oncology, Metastatic Spinal Cord Compression and Cancer of Unknown Primary
    • Brain and Central Nervous System
    • Breast
    • Children's
    • Colorectal
    • Gynaecology
    • Haematology
    • Head and Neck
    • Hepatobiliary (HPB)
    • Lung
    • Neuroendocrine (NET)
    • Non-Specific Symptoms (NSS)
    • Primary Care
    • Psychosocial
    • Radiotherapy
    • Systemic Anti-Cancer Therapy (SACT)
    • Sarcoma
    • Skin
    • Teenage and Young Adults (TYA)
    • Upper Gastrointestinal
    • Urology
  • Operational Delivery Network
    • Pathology
  • Performance Standards
    • The Cancer Dashboard
    • Faster Diagnosis Standard
    • Best Practice Timed Pathway
  • Midlands Cancer Alliances Life Sciences Hub

Acute Oncology, Metastatic Spinal Cord Compression and Cancer of Unknown Primary (AO, MSCC and CUP)

Acute Oncology Services (AOS) aim to provide a co-ordinated approach to the care of cancer patients attending emergency departments (EDs) or who are admitted to hospital non-electively by another route with the following presentations:

  • Complications caused by the systemic treatment of cancer
  • Complications caused by radiotherapy
  • Complications caused by malignant disease, whether the primary site is known or unknown, and presenting as an acute problem or oncological emergency
  • Patients who present with a previously undiagnosed cancer.

Patients with Cancer of Unknown Primary usually present with metastatic disease (secondary cancer) and despite further investigation, the primary site of the cancer cannot be established. Metastatic Spinal Cord Compression (MSCC) happens as a result of cancer spreading into or near the spine, which can then cause pressure onto the spinal cord. There are pathways for the management of patients who present with symptoms suspicious of MSCC. These patients are treated as a medical emergency as, if left untreated, MSCC can lead to paralysis.

AOS were developed in response to two reports, the National Confidential Enquiry into Patient Outcome and Death and a report by the National Chemotherapy Advisory Group, along with the Measures for Cancer Services (Peer Review). The recommendations from these reports have been embodied into the concept of AOS, aimed at ensuring a systematic approach is taken to dealing with cancer related emergencies.

The Acute Oncology Expert Advisory Group (EAG) will be the Cancer Alliance’s primary source of advice on issues relating to acute oncology provision. The AOS EAG overall aims are to provide specialist advice and guidance to the West Midlands Cancer Alliance on the standards of service for patients reflecting current best practice and opportunities for development.

The AOS group and its MSCC sub-group will aim to ensure that patients receive high quality, equitable care throughout the West Midlands regardless of geography or socio-economic factors and will, wherever possible, endeavour to improve the standard of care provided.

Chair: Michael Tilby, Consultant Medical Oncologist, University Hospitals Coventry and Warwickshire NHS Trust

Deputy Chair: Hollie Ellerington, Acute Oncology Advanced Nurse Practitioner and Cancer of Unknown Primary Clinical Nurse Specialist, University Hospitals Coventry and Warwickshire NHS Trust

Documents:

WMCA MUO CUP Guideline v4.0 April 2026 Final.pdf
Popular
WMCA Acute Oncology Directory April 2026
Popular
Malignancy of Unknown Origin and Cancer of Unknown Primary MDT Referral Proforma (July 2025 - V1)
Popular
Standard Operating Procedure (SOP) for the Oncology and Haematology 24-hour Advice Line v2.0 May 2024
Popular
WMCA MUO & CUP Guideline v3.0 December 2023
Popular
Patient Information Leaflet: COVID-19 Vaccines for Cancer Patients receiving treatment V4 October 2023
Popular
MUO & CUP Diagnosis and Management NICE guideline CG104 26 April 2023
Popular
Spinal Metastases & Metastatic Spinal Cord Compression NICE guideline NG234 06 Sept 2023
Popular
UKONS Acute Oncology Initial Management Guidelines V4 Feb 2023
Popular
WMCA Guidelines for Referral of Patients with Spinal Metastatic Disease V3 April 2022
Popular
WMCA MSCC Mobilisastion Rehab Protocol V1 April 2022
Popular
Clinical Advice for the Provision of Acute Oncology Services October 2017
Popular

Contact Us

West Midlands Cancer Alliance
23 Stephenson Street
Birmingham
B2 4BJ

rwh-tr.wmcanceralliance@nhs.net

@NHS_WMCA

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